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Table of Contents
6
1 Description
8
1.1 Terminology
8
1.2 Definitions
8
1.3 Epidemiology
15
1.3.1 Age Cohort
15
1.3.2 Gender
17
1.3.3 Summary
20
1.4 Course and Prognosis
20
1.5 Differential Diagnosis
22
1.6 Comorbidities
23
1.7 Diagnostic Procedures and Documentation
24
1.7.1 Diagnostic Interviews: Semistructured and Structured
25
1.7.2 Clinician Rating Scales
26
1.7.3 Scales Measuring Constructs Related to Depression
28
1.7.4 Depression Scales
32
1.7.5 Inventories with Depression Scales
34
1.7.6 Behavioral Measures
37
2 Theories and Models of the Disorder
40
2.1 Biological Models
40
2.1.1 Genetics
40
2.1.2 Monoamine Hypotheses
41
2.1.3 Neuroendocrine Models
43
2.1.4 Brain-Derived Neurotrophic Factor
43
2.1.5 Biological Rhythms
44
2.2 Psychodynamic Models
44
2.3 Behavioral Models
45
2.4 Interpersonal and Social Skill Models
46
2.5 Interpersonal Psychotherapy
47
2.6 Learned Helplessness
48
2.7 The Cognitive Therapy Model
49
2.8 Self-Management
50
2.9 Concluding Comments
51
3 Diagnosis and Treatment Indications
52
3.1 Dimensions and Subtypes of Depression
52
3.2 Personality Factors as Treatment Indicators
53
3.3 Life Events and Stress
56
4 Treatment
58
4.1 Methods of Treatment
58
4.1.1 Therapy Packages
58
4.1.2 Education About Depression
59
4.1.3 Behavioral Activation
61
4.1.4 Scheduling as an Intervention
62
4.1.5 Continuous Assessment
62
4.1.6 Skill Training
63
4.1.7 Problem Solving
63
4.1.8 Interpersonal Psychotherapy
64
4.1.9 Countering Helplessness
65
4.1.10 Cognitive Techniques
66
4.1.11 Mindfulness
68
4.1.12 Goal Setting
69
4.1.13 Self-Reinforcement/Self-Talk
70
4.1.14 Assets List
70
4.1.15 Other Psychotherapy Components
71
4.1.16 Medications
72
4.2 Mechanisms of Action
73
4.3 Efficacy and Prognosis
75
4.3.1 Efficacy
75
4.3.2 Prognosis and Relapse
77
4.4 Variations and Combinations of Treatments
77
4.4.1 Applications to Different Populations
77
4.4.2 Treatment Formats
78
4.4.3 Sequencing with Medication
78
4.5 Problems in Carrying Out the Treatments
79
4.6 Multicultural Issues
80
5 Further Reading
81
6 References
85
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