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Preface
5
Contents
8
1 Introduction
13
1.1 Computed Tomography – State of the Art
13
1.2 Inverse Problems
14
1.3 Historical Perspective
16
1.4 Some Examples
19
1.5 Structure of the Book
23
2 FundamentalsofX-rayPhysics
26
2.1 Introduction
26
2.2 X- ray Generation
26
2.3 Photon–Matter Interaction
42
2.4 Problems with Lambert–Beer’s Law
57
2.5 X- ray Detection
59
2.6 X- ray Photon Statistics
70
3 Milestones of Computed Tomography
85
3.1 Introduction
85
3.2 Tomosynthesis
86
3.3 Rotation– Translation of a Pencil Beam(First Generation)
89
3.4 Rotation– Translation of a Narrow Fan Beam (Second Generation)
93
3.5 Rotation of aWide Aperture Fan Beam ( Third Generation)
94
3.6 Rotation–Fix with Closed Detector Ring (Fourth Generation)
97
3.7 Electron BeamComputerized Tomography
99
3.8 Rotation in Spiral Path
100
3.9 Rotation in Cone-BeamGeometry
101
3.10 Micro- CT
103
3.11 PET- CT Combined Scanners
106
3.12 Optical Reconstruction Techniques
108
4 Fundamentals of Signal Processing
110
4.1 Introduction
111
4.2 Signals
111
4.3 Fundamental Signals
111
4.4 Systems
113
4.5 Signal Transmission
115
4.6 Dirac’s Delta Distribution
118
4.7 Dirac Comb
121
4.8 Impulse Response
124
4.9 Transfer Function
125
4.10 Fourier Transform
127
4.11 Convolution Theorem
133
4.12 Rayleigh’s Theorem
134
4.13 Power Theorem
134
4.14 Filtering in the Frequency Domain
135
4.15 Hankel Transform
137
4.16 Abel Transform
141
4.17 Hilbert Transform
142
4.18 Sampling Theoremand Nyquist Criterion
144
4.19 Wiener–Khintchine Theorem
150
4.20 Fourier Transform of Discrete Signals
153
4.21 Finite Discrete Fourier Transform
154
4.22 z- Transform
156
4.23 Chirp z- Transform
157
5 Two-Dimensional Fourier-Based ReconstructionMethods
160
5.1 Introduction
160
5.2 Radon Transformation
162
5.3 Inverse Radon Transformation and Fourier Slice Theorem
172
5.4 Implementation of the Direct Inverse Radon Transform
176
5.5 LinogramMethod
179
5.6 Simple Backprojection
184
5.7 Filtered Backprojection
188
5.8 Comparison Between Backprojection and Filtered Backprojection
192
5.9 Filtered Layergram: Deconvolution of the Simple Backprojection
196
5.10 Filtered Backprojection and Radon’s Solution
200
5.11 Cormack Transform
203
6 Algebraic and Statistical ReconstructionMethods
210
6.1 Introduction
210
6.2 Solution with Singular Value Decomposition
216
6.3 Iterative Reconstruction with ART
220
6.4 Pixel Basis Functions and Calculation of the SystemMatrix
227
6.5 Maximum Likelihood Method
232
7 Technical Implementation
250
7.1 Introduction
250
7.2 Reconstruction with Real Signals
251
7.3 Practical Implementation of the Filtered Backprojection
264
7.4 Minimum Number of Detector Elements
267
7.5 Minimum Number of Projections
268
7.6 Geometry of the Fan-Beam System
270
7.7 Image Reconstruction for Fan-Beam Geometry
271
7.8 Quarter-Detector Offset and Sampling Theorem
302
8 Three-Dimensional Fourier-Based ReconstructionMethods
311
8.1 Introduction
311
8.2 Secondary Reconstruction Based on 2D Stacks of Tomographic Slices
312
8.3 Spiral CT
317
8.4 Exact 3D Reconstruction in Parallel-Beam Geometry
329
8.5 Exact 3D Reconstruction in Cone-Beam Geometry
344
8.6 Approximate 3D Reconstructions in Cone-BeamGeometry
374
8.7 Helical Cone-Beam Reconstruction Methods
402
9 Image Quality and Artifacts
410
9.1 Introduction
410
9.2 Modulation Transfer Function of the Imaging Process
411
9.3 Modulation Transfer Function and Point Spread Function
417
9.4 Modulation Transfer Function in Computed Tomography
419
9.5 SNR, DQE, and ROC
428
9.6 2D Artifacts
430
9.7 3D Artifacts
452
9.8 Noise in Reconstructed Images
469
10 Practical Aspects of Computed Tomography
477
10.1 Introduction
477
10.2 Scan Planning
477
10.3 Data Representation
481
10.4 Some Applications in Medicine
488
11 Dose
491
11.1 Introduction
491
11.2 Energy Dose, Equivalent Dose, and Effective Dose
492
11.3 Definition of Specific CT Dose Measures
493
11.4 Device-Related Measures for Dose Reduction
499
11.5 User-Related Measures for Dose Reduction
505
References
509
Subject Index
516
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